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Dysregulation of metallothionein and circadian genes in human hepatocellular carcinoma

20 Dec 2016

Abstract excerpt

Hepatocellular carcinoma (HCC) is the major threat to human health, and disruption of circadian clock genes is implicated in hepatocarcinogenesis. This study examined the dysregulation of metallothioneins and circadian genes in achieved human HCC (n = 24), peri-HCC tissues (n = 24) as compared with normal human livers (n = 36). Total RNA was extracted and reverse transcribed. Real-time RT-qPCR was performed to...

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PMID: 27997226
DOI: 10.1080/07420528.2016.1256300

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