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Article

Metallothionein 1G functions as a tumor suppressor in thyroid cancer through modulating the PI3K/Akt signaling pathway

8 Oct 2013

Abstract excerpt

BACKGROUND: MT1G inactivation mediated by promoter methylation has been reported in thyroid cancer. However, the role of MT1G in thyroid carcinogenesis remains unclear. The aim of this study is to examine the biological functions and related molecular mechanisms of MT1G in thyroid cancer. METHODS: Methylation-specific PCR (MSP) was performed to analyze promoter methylation of MT1G and its relationship with...

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PMID: 24098937
DOI: 10.1186/1471-2407-13-462

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