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Article

A knowledge-based method for association studies on complex diseases.

PloS one - 1 Jan 2012

Nazarian Alireza, Sichtig Heike, Riva Alberto

Abstract excerpt

Complex disorders are a class of diseases whose phenotypic variance is caused by the interplay of multiple genetic and environmental factors. Analyzing the complexity underlying the genetic architecture of such traits may help develop more efficient diagnostic tests and therapeutic protocols. Despite the continuous advances in revealing the genetic basis of many of complex diseases using genome-wide association...

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Identifiers

PMID: 22970175
DOI: 10.1371/journal.pone.0044162
PMCID: PMC3435396

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