Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beyond GWAS: from simple associations to functional insights.

Seminars in immunopathology - 1 Jan 2022

Ishigaki Kazuyoshi

Abstract excerpt

Each human, when born, has slightly different DNA sequences, which make each of us unique. The variations in DNA sequences are called genetic variants. The primary aim of genome-wide association study (GWAS) is to detect associations between genetic variants and human phenotypes. Since GWAS focuses on germ-line variants, there is no reverse causation. Therefore, GWAS is one of the few tools that can assess the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Autoimmune Diseases
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 34605948
DOI: 10.1007/s00281-021-00894-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beyond GWAS: from simple associations to functional insights.PMID 34605948Read ↗

Genetics of rheumatoid arthritis: GWAS and beyondSemantic proximity Read ↗

Five years of GWAS discovery.Semantic proximity Read ↗

Performing post-genome-wide association study analysis: overview, challenges and recommendationsSemantic proximity Read ↗

Chapter 11: Genome-wide association studies.Semantic proximity Read ↗

What have we learned from six years of GWAS in autoimmune diseases, and what is next?Semantic proximity Read ↗

Do genome-wide association scans have potential for translation?Semantic proximity Read ↗

Concepts and relevance of genome-wide association studies.Semantic proximity Read ↗

Genome-wide association studies: results from the first few years and potential implications for clinical medicine.Semantic proximity Read ↗

[Genome-wide association studies: methodology and interpretation for clinicians].Semantic proximity Read ↗

Bringing genome-wide association findings into clinical use.Semantic proximity Read ↗

GWAShug: a comprehensive platform for decoding the shared genetic basis between complex traits based on summary statistics.Semantic proximity Read ↗

10 Years of GWAS Discovery: Biology, Function, and Translation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.