Chimerism analysis in transplant patients: a hypothesis-free approach in the absence of reference genotypes.

Abstract excerpt

INTRODUCTION: During routine analysis of chimerism in bone marrow transplant patients pre-transplant genotype of the recipient or the donor might lack. We aimed to develop a new method to analyze DNA results suitable when reference genotypes are not available. METHODS: The method was based on the balance between heterozygotes. It was implemented in a standard computer spreadsheet, and considered the hypothetical...

Topics

Join the communities discussing this publication.

• Algorithms
• Autoanalysis
• Bone Marrow Transplantation
• Computational Biology
• DNA