Article
An archaeal sRNA targeting cis- and trans-encoded mRNAs via two distinct domains.
Nucleic acids research - 1 Nov 2012
Jäger Dominik, Pernitzsch Sandy R, Richter Andreas S, Backofen Rolf, Sharma Cynthia M, Schmitz Ruth A
Abstract excerpt
We report on the characterization and target analysis of the small (s)RNA(162) in the methanoarchaeon Methanosarcina mazei. Using a combination of genetic approaches, transcriptome analysis and computational predictions, the bicistronic MM2441-MM2440 mRNA encoding the transcription factor MM2441 and a protein of unknown function was identified as a potential target of this sRNA, which due to processing...
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