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Article

Genome-Wide Analysis of Pain-, Nerve- and Neurotrophin -Related Gene Expression in the Degenerating Human Annulus

1 Jan 2012

Abstract excerpt

BACKGROUND: In spite of its high clinical relevance, the relationship between disc degeneration and low back pain is still not well understood. Recent studies have shown that genome-wide gene expression studies utilizing ontology searches provide an efficient and valuable methodology for identification of clinically relevant genes. Here we use this approach in analysis of pain-, nerve-, and neurotrophin-related...

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PMID: 22963171
DOI: 10.1186/1744-8069-8-63

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