Article
Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function.
PloS one - 1 Jan 2012
Oommen Shelly, Francois Mathias, Kawasaki Maiko, Murrell Melanie, Kawasaki Katsushige, Porntaveetus Thantrira, Ghafoor Sarah, Young Neville J, Okamatsu Yoshimasa, McGrath John, Koopman Peter, Sharpe Paul T, Ohazama Atsushi
Abstract excerpt
Hemidesmosomes are composed of intricate networks of proteins, that are an essential attachment apparatus for the integrity of epithelial tissue. Disruption leads to blistering diseases such as epidermolysis bullosa. Members of the Sox gene family show dynamic and diverse expression patterns during development and mutation analyses in humans and mice provide evidence that they play a remarkable variety of roles...
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