Article
Investigation of the vitamin D receptor gene (VDR) and its interaction with protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2) on risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY).
The Journal of steroid biochemistry and molecular biology - 1 Jan 2013
Frederiksen B, Liu E, Romanos J, Steck A K, Yin X, Kroehl M, Fingerlin T E, Erlich H, Eisenbarth G S, Rewers M, Norris J M
Abstract excerpt
The present study investigated the association between variants in the vitamin D receptor gene (VDR) and protein tyrosine phosphatase, non-receptor type 2 gene (PTPN2), as well as an interaction between VDR and PTPN2 and the risk of islet autoimmunity (IA) and progression to type 1 diabetes (T1D). The Diabetes Autoimmunity Study in the Young (DAISY) has followed children at increased risk of T1D since 1993. Of...
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