Article
Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium.
Virology - 25 Nov 2012
Schaap-Nutt Anne, Liesman Rachael, Bartlett Emmalene J, Scull Margaret A, Collins Peter L, Pickles Raymond J, Schmidt Alexander C
Abstract excerpt
Human parainfluenza viruses (PIVs) cause acute respiratory illness in children, the elderly, and immunocompromised patients. PIV3 is a common cause of bronchiolitis and pneumonia, whereas PIV1 and 2 are frequent causes of upper respiratory tract illness and croup. To assess how PIV1, 2, and 3 differ with regard to replication and induction of type I interferons, interleukin-6, and relevant chemokines, we infected...
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