Article

Ascending vaginal infection in mice induces preterm birth and neonatal morbidity

2023-08-14

Abstract excerpt

Preterm birth (PTB; delivery <37 weeks), the main cause of neonatal death worldwide, can lead to adverse neurodevelopmental outcomes, as well as lung and gut pathology. PTB is commonly associated with ascending vaginal infection. Previously, we have shown that ascending E. coli infection in pregnant mice induces PTB and reduces pup survival. Here, we demonstrate that this model recapitulates the pathology observe...

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Literature Corpus work: 67409d91-be6c-5988-b725-1b885e5fced9
DOI: 10.1101/2023.08.14.553220

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