Inhibition of autoimmune disease in a murine model of systemic lupus erythematosus induced by exposure to syngeneic photoinactivated lymphocytes.

doi:10.1111/1523-1747.ep12873349

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Article

Inhibition of autoimmune disease in a murine model of systemic lupus erythematosus induced by exposure to syngeneic photoinactivated lymphocytes.

The Journal of investigative dermatology - 1 Jan 1990

Berger C L, Perez M, Laroche L, Edelson R

Abstract excerpt

MRL/l mice develop progressive, virulent autoimmune disease that has many of the features of systemic lupus erythematosus. Prophylactic treatment of MRL/l mice with syngeneic photoinactivated autoimmune splenocytes improves survival and inhibits the fulminant hyperproliferation of abnormal T cell...

Topics

Animals
Autoantibodies
Autoimmune Diseases
Concanavalin A
DNA
Female
Light
Lipopolysaccharides
Lupus Erythematosus, Systemic
Lymphocyte Activation
Lymphocyte Transfusion
Lymphocytes
Lymphoid Tissue
Mice
Mice, Inbred Strains
Phenotype
Spleen
Survival Analysis

Source

Open in PubMed

Identifiers

PMID: 2295837
DOI: 10.1111/1523-1747.ep12873349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2295837-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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