Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse.

Clinical immunology (Orlando, Fla.) - 1 Sept 1999

Kench J A, Russell D M, Fadok V A, Young S K, Worthen G S, Jones-Carson J, Henson J E, Henson P M, Nemazee D

Abstract excerpt

Wound healing is a complex process that involves inflammation, apoptosis, growth, and tissue remodeling. The autoimmune-prone inbred mouse strain MRL/+ manifests accelerated and extensive healing to ear punch wounds, suggesting a link between immune defects and wound healing. Prior studies with lupus-prone mice have shown that hematopoietic cells of lupus-prone strains can transfer disease to otherwise...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Transplantation
Share to Bronchoalveolar Lavage Fluid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Inflammation Mediators

Share to Mice, Inbred MRL lpr

Share to Neutrophils

Share to Pneumonia

Share to Transplantation Chimera

Share to Wound Healing

Source

Identifiers

PMID: 10479535
DOI: 10.1006/clim.1999.4754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant wound healing and TGF-beta production in the autoimmune-prone MRL/+ mouse.PMID 10479535Read ↗

Severe tissue trauma triggers the autoimmune state systemic lupus erythematosus in the MRL/++ lupus-prone mouse.Semantic proximity Read ↗

Mice with a regenerative wound healing capacity and an SLE autoimmune phenotype contain elevated numbers of circulating and marrow-derived macrophage progenitor cells.Semantic proximity Read ↗

Regeneration in MRL mice: further genetic loci controlling the ear hole closure trait using MRL and M.m. Castaneus mice.Semantic proximity Read ↗

Accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice.Semantic proximity Read ↗

Toll‐like receptor 9 signaling protects against murine lupusSemantic proximity Read ↗

Severer lupus erythematosus-like skin lesions in MRL/lpr mice with homozygous Kitwsh/wsh mutation.Semantic proximity Read ↗

Bone marrow transplantation from mutant lpr/lpr mice. Functional abnormalities rather than alloantigenic differences appear to determine the development of a graft-vs.-host-like syndrome.Semantic proximity Read ↗

Intrinsic defects in macrophage IL-12 production associated with immune dysfunction in the MRL/++ and New Zealand Black/White F1 lupus-prone mice and the Leishmania major-susceptible BALB/c strain.Semantic proximity Read ↗

Heart regeneration in adult MRL mice.Semantic proximity Read ↗

Hypo-active variant of IL-2 and associated decreased T cell activation contribute to impaired apoptosis in autoimmune prone MRL mice.Semantic proximity Read ↗

Mast Cells: A Cellular Link Between Autoantibodies and Inflammatory ArthritisSemantic proximity Read ↗

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.