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<scp>DNA</scp> Methylation/Demethylation Network Expression in Psychotic Patients with a History of Alcohol Abuse

7 Sept 2012

Abstract excerpt

BACKGROUND: Recent studies suggest that protracted and excessive alcohol use induces an epigenetic dysregulation in human and rodent brains. We recently reported that DNA methylation dynamics are altered in brains of psychotic (PS) patients, including schizophrenia and bipolar disorder patients. Because PS patients are often comorbid with chronic alcohol abuse, we examined whether the altered expression of...

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PMID: 22958170
DOI: 10.1111/j.1530-0277.2012.01947.x

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