Article
Identification of genes for complex diseases using integrated analysis of multiple types of genomic data.
PloS one - 1 Jan 2012
Cao Hongbao, Lei Shufeng, Deng Hong-Wen, Wang Yu-Ping
Abstract excerpt
Various types of genomic data (e.g., SNPs and mRNA transcripts) have been employed to identify risk genes for complex diseases. However, the analysis of these data has largely been performed in isolation. Combining these multiple data for integrative analysis can take advantage of complementary information and thus can have higher power to identify genes (and/or their functions) that would otherwise be impossible...
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