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Article

In vivo quantification reveals extensive natural variation in mitochondrial form and function in Caenorhabditis briggsae.

PloS one - 1 Jan 2012

Hicks Kiley A, Howe Dana K, Leung Aubrey, Denver Dee R, Estes Suzanne

Abstract excerpt

We have analyzed natural variation in mitochondrial form and function among a set of Caenorhabditis briggsae isolates known to harbor mitochondrial DNA structural variation in the form of a heteroplasmic nad5 gene deletion (nad5Δ) that correlates negatively with organismal fitness. We performed in vivo quantification of 24 mitochondrial phenotypes including reactive oxygen species level, membrane potential, and...

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Share to Caenorhabditis
Share to DNA, Mitochondrial
Share to Electron Transport Chain Complex Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hybridization, Genetic

Share to Membrane Potential, Mitochondrial

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Source

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Identifiers

PMID: 22952781
DOI: 10.1371/journal.pone.0043837
PMCID: PMC3429487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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