Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CD146 expression in human breast cancer cell lines induces phenotypic and functional changes observed in Epithelial to Mesenchymal Transition.

PloS one - 1 Jan 2012

Imbert Anne-Marie, Garulli Celine, Choquet Elodie, Koubi Myriam, Aurrand-Lions Michel, Chabannon Christian

Abstract excerpt

BACKGROUND: Metastasis is an important step in tumor progression leading to a disseminated and often incurable disease. First steps of metastasis include down-regulation of cell adhesion molecules, alteration of cell polarity and reorganization of cytoskeleton, modifications associated with enhanced migratory properties and resistance of tumor cells to anoikis. Such modifications resemble Epithelial to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Epithelial-Mesenchymal Transition

Share to Gene Expression Regulation, Neoplastic

Share to Neuregulin-1

Share to Receptors, Cell Surface

Share to Receptors, Estrogen

Source

Open in PubMed Open full text

Identifiers

PMID: 22952755
DOI: 10.1371/journal.pone.0043752
PMCID: PMC3431364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CD146 expression in human breast cancer cell lines induces phenotypic and functional changes observed in Epithelial to Mesenchymal Transition.PMID 22952755Read ↗

CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell linesSemantic proximity Read ↗

The role of CD146 (Mel-CAM) in biology and pathologySemantic proximity Read ↗

An In Vitro Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast CancerSemantic proximity Read ↗

CD146 mediates an E-cadherin-to-N-cadherin switch during TGF-β signaling-induced epithelial-mesenchymal transitionSemantic proximity Read ↗

Expression of epithelial-mesenchymal transition-related markers in triple-negative breast cancer: ZEB1 as a potential biomarker for poor clinical outcome.Semantic proximity Read ↗

Phenotype-dependent effects of EpCAM expression on growth and invasion of human breast cancer cell lines.Semantic proximity Read ↗

WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells.Semantic proximity Read ↗

The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolismSemantic proximity Read ↗

E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells.Semantic proximity Read ↗

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancerSemantic proximity Read ↗

Cell Adhesion Molecules: Role and Clinical Significance in CancerSemantic proximity Read ↗

JAM‐A expression positively correlates with poor prognosis in breast cancer patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.