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Article

Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine.

AIDS (London, England) - 23 Oct 2012

Frasco Melissa A, Mack Wendy J, Van Den Berg David, Aouizerat Bradley E, Anastos Kathryn, Cohen Mardge, De Hovitz Jack, Golub Elizabeth T, Greenblatt Ruth M, Liu Chenglong, Conti David V, Pearce Celeste L

Abstract excerpt

OBJECTIVE: CYP2B6 variation predicts pharmacokinetic characteristics of its substrates. Consideration for underlying genetic structure is critical to protect against spurious associations with the highly polymorphic CYP2B6 gene. DESIGN: The effect of CYP2B6 variation on response to its substrates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22951632
DOI: 10.1097/QAD.0b013e3283593602
PMCID: PMC3940150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22951632-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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