Article
An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis.
Blood - 30 Jul 2009
Kälin Roland E, Bänziger-Tobler Nadja E, Detmar Michael, Brändli André W
Abstract excerpt
Angiogenesis and lymphangiogenesis are essential for organogenesis but also play important roles in tissue regeneration, chronic inflammation, and tumor progression. Here we applied in vivo forward chemical genetics to identify novel compounds and biologic mechanisms involved in (lymph)angiogenes...
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