Article
Working memory performance in young adults is associated to the AATn polymorphism of the CNR1 gene.
Behavioural brain research - 1 Jan 2013
Ruiz-Contreras Alejandra E, Carrillo-Sánchez Karol, Gómez-López Nardhy, Vadillo-Ortega Felipe, Hernández-Morales Salvador, Carnevale-Cantoni Alessandra, Espejel-Núñez Aurora, Méndez-Díaz Mónica, Prospéro-García Oscar
Abstract excerpt
Working memory (WM) depends on several neural networks and neurochemical systems. One of them is the endocannabinoid (eCB) system, which CB1 receptor (CB1R) is widely distributed all over the brain. The stimulation of CB1R by agonists reduces WM efficiency. The CNR1 human gene (6q14-15) encodes the CB1R. AATn polymorphism of the CNR1 gene has been related to psychiatric disorders, and to procedural learning and...
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