Article
Performance in working memory and attentional control is associated with the rs2180619 SNP in the CNR1 gene.
Genes, brain, and behavior - 1 Feb 2014
Ruiz-Contreras A E, Carrillo-Sánchez K, Ortega-Mora I, Barrera-Tlapa M A, Román-López T V, Rosas-Escobar C B, Flores-Barrera L, Caballero-Sánchez U, Muñoz-Torres Z, Romero-Hidalgo S, Hernández-Morales S, González-Barrios J A, Vadillo-Ortega F, Méndez-Díaz M, Aguilar-Roblero R, Prospéro-García O
Abstract excerpt
Individual differences in cognitive performance are partly dependent, on genetic polymporhisms. One of the single-nucleotide polymorphisms (SNP) of the CNR1 gene, which codes for cannabinoid receptor 1 (CB1R), is the rs2180619, located in a regulatory region of this gene (6q14-q15). The alleles of the rs2180619 are A > G; the G allele has been associated with addiction and high levels of anxiety (when the G...
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