Article
Genetic risk for schizophrenia, obstetric complications, and adolescent school outcome: evidence for gene-environment interaction.
Schizophrenia bulletin - 1 Sept 2013
Forsyth Jennifer K, Ellman Lauren M, Tanskanen Antti, Mustonen Ulla, Huttunen Matti O, Suvisaari Jaana, Cannon Tyrone D
Abstract excerpt
Low birth weight (LBW) and hypoxia are among the environmental factors most reliably associated with schizophrenia; however, the nature of this relationship is unclear and both gene-environment interaction and gene-environment covariation models have been proposed as explanations. High-risk (HR) designs that explore whether obstetric complications differentially predict outcomes in offspring at low risk (LR) vs...
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