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Article

The Relationship between Gastroduodenal Pathologies and Helicobacter pylori cagL (Cytotoxin-Associated Gene L) Polymorphism.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Apr 2023

Özbey Doğukan, Demiryas Süleyman, Akkuş Seher, Kepil Nuray, Dinç Harika Öykü, Gareayaghi Nesrin, Demirci Mehmet, Kurt Enes Ali, Uysal Ömer, Sarıbaş Suat, Tokman Hrisi Bahar, Kocazeybek Bekir

Abstract excerpt

BACKGROUND: The polymorphisms in the region between 58 and 62 amino acids of the 194-amino acid CagL protein (CagL hypervariable motif) affect the binding affinity of CagL to integrin α5β1 (ITGA5B1) receptor in host epithelial cells and have an effect on the development of various gastrointestinal diseases. We aimed to evaluate the associations of gastroduodenal pathologies, with the polymorphisms of cagL gene of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36789984
DOI: 10.5152/tjg.2023.22274
PMCID: PMC10210604

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