A RAND/UCLA appropriateness study of the management of familial gastric cancer.

doi:10.1245/s10434-012-2584-z

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Article

A RAND/UCLA appropriateness study of the management of familial gastric cancer.

Annals of surgical oncology - 1 Feb 2013

Dixon Matthew, Seevaratnam Rajini, Wirtzfeld Debrah, McLeod Robin, Helyer Lucy, Law Calvin, Swallow Carol, Paszat Lawrence, Bocicariu Alina, Cardoso Roberta, Mahar Alyson, Bekaii-Saab Tanios, Chau Ian, Church Neal, Coit Daniel, Crane Christopher H, Earle Craig, Mansfield Paul, Marcon Norman, Miner Thomas, Noh Sung Hoon, Porter Geoff, Posner Mitchell C, Prachand Vivek, Sano Takeshi, Van de Velde Cornelis J H, Wong Sandra, Coburn Natalie

Abstract excerpt

BACKGROUND: Hereditary diffuse gastric cancer (HDGC) represents a minority of gastric cancer (GC) cases. The goal of this study is to use a RAND/University of California Los Angeles (UCLA) appropriateness methodology to examine indications for genetic referral, CDH1 testing, and consideration of prophylactic total gastrectomy (PTG). METHODS: A multidisciplinary expert panel of 16 physicians from six countries...

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PMID: 22941158
DOI: 10.1245/s10434-012-2584-z

Genes

CDH1

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