Article
Differences in genomic architecture between two distinct geographical strains of the blood fluke Schistosoma japonicum reveal potential phenotype basis.
Molecular and cellular probes - 1 Feb 2013
Gobert Geoffrey N, You Hong, Jones Malcolm K, McInnes Russell, McManus Donald P
Abstract excerpt
The Chinese (SjC) and Philippine (SjP) strains of the blood fluke Schistosoma japonicum have been shown to present clearly different phenotypes in fecundity, pathology, drug sensitivity and immunology. We used microarray based comparative genomic hybridisation (aCGH) to investigate structural differences in the genomes of the two strains and identified seven distinct regions of the S. japonicum genome that...
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