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Article

Evolution of antigenic diversity in the zoonotic multi-host parasite Schistosoma japonicum: implications for vaccine design.

International journal for parasitology - 1 Jul 2025

Parsons Daniel A J, Walker Anthony J, Emery Aidan M, Allan Fiona, Lu Da-Bing, Webster Joanne P, Lawton Scott P

Abstract excerpt

The multi-host zoonotic transmission of the blood fluke Schistosoma japonicum is complex, presenting challenges for China's schistosomiasis elimination strategy. How multi-host transmission impacts the genetic diversity of S. japonicum populations is poorly understood and the extent of Schistosoma japonicum antigen coding gene (SjACG) variability remains unknown despite the implications for parasite survival,...

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PMID: 40204227
DOI: 10.1016/j.ijpara.2025.04.004

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