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Article

Comparative genomics of Plasmodium yoelii nigeriensis N67 and N67C: genome-wide polymorphisms, differential gene expression, and drug resistance.

BMC genomics - 5 Nov 2024

Wu Jian, Oguz Cihan, Teklemichael Awet Alem, Xu Fangzheng, Stadler Rachel V, Lucky Amuza Byaruhanga, Liu Shengfa, Kaneko Osamu, Lack Justin, Su Xin-Zhuan

Abstract excerpt

BACKGROUND: The study of rodent malaria parasites has significantly advanced our understanding of malaria parasite biology and host responses to parasite infections. There are four well-characterized rodent malaria parasite species (Plasmodium yoelii, P. chabaudi, P. berghei, and P. vinckei). Each species also has multiple strains that cause different disease phenotypes. P. yoelii nigeriensis N67C and N67, two...

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PMID: 39497038
DOI: 10.1186/s12864-024-10961-4
PMCID: PMC11536827

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