Article
Lack of resistance-associated mutations in UL54 and UL97 genes of circulating cytomegalovirus strains isolated in a medical center in Taiwan.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Aug 2012
Shao Pei-Lan, Lu Meng-You, Liau Yi-Jen, Kao Chuan-Liang, Chang Shu-Yuan, Huang Li-Min
Abstract excerpt
Human cytomegalovirus (HCMV) is a large DNA virus and a member of the betaherpesvirus family. HCMV infection is extremely common in human populations and can cause severe diseases in immunocompromised hosts. Ganciclovir is the most widely used antiviral drug for cytomegalovirus infection and works by blocking the amplification of HCMV. HCMV strains resistant to ganciclovir have been detected in recent decades and...
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