Article
Molecular Analysis of Ganciclovir-Resistant Cytomegalovirus in Renal Transplant Recipients with High Viral Load.
Archives of Iranian medicine - 1 Oct 2016
Sohrabi Majid, Behzadian Farida, Hosseini Seied Mohammad Javad, Lashini Hadi
Abstract excerpt
BACKGROUND: Gancyclovir-resistant (GanR) cytomegalovirus (CMV) remains an issue, especially in solid organ transplant (SOT) recipients. Some mutations in UL54 and UL97 confer this resistance. Long-lasting high-dose drug exposure, high viral load, together with lack of sufficient compliance with treatment may account for these mutations. The aim of this study was to detect UL97 and UL54 putative mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
