Article
Red cell and platelet-derived microparticles are increased in G6PD-deficient subjects.
European journal of haematology - 1 Nov 2012
Nantakomol Duangdao, Palasuwan Attakorn, Chaowanathikhom Mallika, Soogarun Suphan, Imwong Mallika
Abstract excerpt
In response to oxidative stress and during apoptosis, cells often shed microparticles (MPs), submicron elements carrying phosphatidylserine and protein antigens. Glucose-6-phosphate dehydrogenase (G6PD)-deficient cells are extremely sensitive to oxidative damage that may lead to the formation of MPs. To determine whether G6PD deficiency alters membrane phospholipid asymmetry and increases MPs production, we...
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