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Article

Changes in red blood cell membrane structure in G6PD deficiency: an atomic force microscopy study.

Clinica chimica acta; international journal of clinical chemistry - 15 Apr 2015

Tang Jia, Jiang Chengrui, Xiao Xiao, Fang Zishui, Li Lei, Han Luhao, Mei Anqi, Feng Yi, Guo Yibin, Li Hongyi, Jiang Weiying

Abstract excerpt

BACKGROUND: Glucose-6-phosphate dehydrogenase deficiency affects over 400 million people worldwide. The hemolytic anemia in G6PD deficiency is usually triggered by oxidative stress, but the mechanism remains uncertain. We have used atomic force microscopy for studying changes in red blood cell membrane and providing new insights on the mechanism. METHODS: G6PD activity assay and molecular genetic tests were used...

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PMID: 25748035
DOI: 10.1016/j.cca.2015.02.042

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AFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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