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Article

Zebrafish foxP2 zinc finger nuclease mutant has normal axon pathfinding.

PloS one - 1 Jan 2012

Xing Lingyan, Hoshijima Kazuyuki, Grunwald David J, Fujimoto Esther, Quist Tyler S, Sneddon Jacob, Chien Chi-Bin, Stevenson Tamara J, Bonkowsky Joshua L

Abstract excerpt

foxP2, a forkhead-domain transcription factor, is critical for speech and language development in humans, but its role in the establishment of CNS connectivity is unclear. While in vitro studies have identified axon guidance molecules as targets of foxP2 regulation, and cell culture assays suggest a role for foxP2 in neurite outgrowth, in vivo studies have been lacking regarding a role for foxP2 in axon...

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Identifiers

PMID: 22937139
DOI: 10.1371/journal.pone.0043968
PMCID: PMC3427223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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