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Article

Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits.

American journal of human genetics - 1 Jun 2005

MacDermot Kay D, Bonora Elena, Sykes Nuala, Coupe Anne-Marie, Lai Cecilia S L, Vernes Sonja C, Vargha-Khadem Faraneh, McKenzie Fiona, Smith Robert L, Monaco Anthony P, Fisher Simon E

Abstract excerpt

FOXP2, the first gene to have been implicated in a developmental communication disorder, offers a unique entry point into neuromolecular mechanisms influencing human speech and language acquisition. In multiple members of the well-studied KE family, a heterozygous missense mutation in FOXP2 cause...

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Identifiers

PMID: 15877281
DOI: 10.1086/430841
PMCID: PMC1196445

Genes

FOXP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15877281-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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