Article
Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
Human molecular genetics - 1 Dec 2012
Jin Guangfu, Sun Jielin, Kim Seong-Tae, Feng Junjie, Wang Zhong, Tao Sha, Chen Zhuo, Purcell Lina, Smith Shelly, Isaacs William B, Rittmaster Roger S, Zheng S Lilly, Condreay Lynn D, Xu Jianfeng
Abstract excerpt
Circulating androgen levels are often used as indicators of physiological or pathological conditions. More than half of the variance for circulating androgen levels is thought to be genetically influenced. A genome-wide association study (GWAS) has identified two loci, SHBG at 17p13 and FAM9B at Xp22, for serum testosterone (T) levels; however, these explain only a small fraction of inter-individual variability....
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