Article
Bioenergetic role of mitochondrial fusion and fission.
Biochimica et biophysica acta - 1 Oct 2012
Westermann Benedikt
Abstract excerpt
Mitochondria are highly dynamic organelles. Frequent cycles of fusion and fission adapt the morphology of the mitochondrial compartment to the metabolic needs of the cell. Mitochondrial fusion is particularly important in respiratory active cells. It allows the spreading of metabolites, enzymes, and mitochondrial gene products throughout the entire mitochondrial compartment. This serves to optimize mitochondrial...
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