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Mitochondrial Dynamics: Fission and Fusion in Fate Determination of Mesenchymal Stem Cells

15 Oct 2020

Abstract excerpt

Mesenchymal stem cells (MSCs) are pivotal to tissue homeostasis, repair, and regeneration due to their potential for self-renewal, multilineage differentiation, and immune modulation. Mitochondria are highly dynamic organelles that maintain their morphology via continuous fission and fusion, also known as mitochondrial dynamics. MSCs undergo specific mitochondrial dynamics during proliferation, migration,...

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PMID: 33178694
DOI: 10.3389/fcell.2020.580070

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