Article
Interactions between genetic background, insulin resistance and β-cell function.
Diabetes, obesity & metabolism - 1 Oct 2012
Kahn S E, Suvag S, Wright L A, Utzschneider K M
Abstract excerpt
An interaction between genes and the environment is a critical component underlying the pathogenesis of the hyperglycaemia of type 2 diabetes. The development of more sophisticated techniques for studying gene variants and for analysing genetic data has led to the discovery of some 40 genes associated with type 2 diabetes. Most of these genes are related to changes in β-cell function, with a few associated with...
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