Article
Genetics: how the UKPDS contributed to determining the genetic landscape of Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association - 1 Aug 2008
Gloyn A L, McCarthy M I
Abstract excerpt
The identification and functional characterisation of genetic variants that either cause or predispose to diabetes is a major focus of biomedical research. The molecular basis is now known for the majority of monogenic forms of diabetes arising from pancreatic beta-cell dysfunction; however finding the genetic variants underlying susceptibility to Type 2 diabetes (T2DM) has been a greater technical, statistical...
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