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Article

Mex3c mutation reduces adiposity and increases energy expenditure.

Molecular and cellular biology - 1 Nov 2012

Jiao Yan, George Sunil K, Zhao Qingguo, Hulver Matthew W, Hutson Susan M, Bishop Colin E, Lu Baisong

Abstract excerpt

The function of MEX3C, the mammalian homolog of Caenorhabditis elegans RNA-binding protein muscle excess 3 (MEX-3), was unknown until our recent report that MEX3C is necessary for normal postnatal growth and enhances the expression of local bone Igf1 expression. Here we report the pivotal role of Mex3c in energy balance regulation. Mex3c mutation caused leanness in both heterozygous and homozygous transgenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22927639
DOI: 10.1128/MCB.00452-12
PMCID: PMC3486154

Genes

NPY
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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