Article
Pathogenesis of ANCA-associated vasculitis.
Current rheumatology reports - 1 Dec 2012
Cartin-Ceba Rodrigo, Peikert Tobias, Specks Ulrich
Abstract excerpt
Antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitides (AAV) are a group of systemic vasculitis syndromes characterized by inflammation and necrosis of blood vessel walls. Genetic, epigenetic, and environmental factors contribute to the etiology and pathogenesis of AAV. On the basis of currently available clinical and experimental evidence, it is reasonable to believe that, in predisposed...
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