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Article

New insights into the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis.

Autoimmunity reviews - 1 Feb 2002

Kallenberg Cees G M, Rarok Agnieszka, Stegeman Coen A, Limburg Pieter C

Abstract excerpt

Antineutrophil cytoplasmic autoantibodies (ANCA) directed to proteinase 3 (PR3-ANCA) or myeloperoxidase (MPO-ANCA) are closely associated with the idiopathic systemic necrotizing vasculitides, in particular Wegener's granulomatosis, microscopic polyangiitis and its renal limited manifestation, and Churg Strauss Syndrome. Many in vitro studies show that those ANCA have phlogistic potential, particularly at the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12849060
DOI: 10.1016/s1568-9972(01)00008-8

Genes

MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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