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Article

Identification of a lactate-quinone oxidoreductase in Staphylococcus aureus that is essential for virulence.

Frontiers in cellular and infection microbiology - 1 Jan 2011

Fuller James R, Vitko Nicholas P, Perkowski Ellen F, Scott Eric, Khatri Dal, Spontak Jeffrey S, Thurlow Lance R, Richardson Anthony R

Abstract excerpt

Staphylococcus aureus is an important human pathogen commonly infecting nearly every host tissue. The ability of S. aureus to resist innate immunity is critical to its success as a pathogen, including its propensity to grow in the presence of host nitric oxide (NO·). Upon exogenous NO· exposure, S. aureus immediately excretes copious amounts of L-lactate to maintain redox balance. However, after prolonged...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22919585
DOI: 10.3389/fcimb.2011.00019
PMCID: PMC3417369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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