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Article

Readressing the role of Toll-like receptor-4 alleles in inflammatory bowel disease: colitis, smoking, and seroreactivity.

Digestive diseases and sciences - 1 Feb 2013

Manolakis Anastassios C, Kapsoritakis Andreas N, Kapsoritaki Anastasia, Tiaka Elisavet K, Oikonomou Konstantinos A, Lotis Vassilis, Vamvakopoulou Dimitra, Davidi Ioanna, Vamvakopoulos Nikolaos, Potamianos Spyros P

Abstract excerpt

BACKGROUND: Toll-like receptor (TLR) polymorphisms, and especially TLR-4 Asp299Gly and TLR-4 Thr399Ile, have been linked with Crohn's disease (CD) and to a lesser extent with ulcerative colitis (UC), CD behavior, and compromised seroreactivity to microbial antigens. Available data, however, are c...

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PMID: 22918682
DOI: 10.1007/s10620-012-2348-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22918682-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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