Article
NOD2 mutations and anti-Saccharomyces cerevisiae antibodies are risk factors for Crohn's disease in African Americans.
The American journal of gastroenterology - 1 Feb 2010
Dassopoulos Themistocles, Nguyen Geoffrey C, Talor Monica Vladut, Datta Lisa Wu, Isaacs Kim L, Lewis James D, Gold Michael S, Valentine John F, Smoot Duane T, Harris Mary L, Oliva-Hemker Maria, Bayless Theodore M, Burek C Lynne, Brant Steven R
Abstract excerpt
OBJECTIVES: NOD2 mutations and anti-Saccharomyces cerevisiae antibodies (ASCAs) are established risk factors of Crohn's disease (CD) in whites but have not been assessed in African-American (AA) adults with CD. METHODS: AAs with CD and controls were recruited by the Mid-Atlantic African-American IBD Study as part of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) IBD Genetics...
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