Article
Origins of albino and hooded rats: implications from molecular genetic analysis across modern laboratory rat strains.
PloS one - 1 Jan 2012
Kuramoto Takashi, Nakanishi Satoshi, Ochiai Masako, Nakagama Hitoshi, Voigt Birger, Serikawa Tadao
Abstract excerpt
Albino and hooded (or piebald) rats are one of the most frequently used laboratory animals for the past 150 years. Despite this fact, the origin of the albino mutation as well as the genetic basis of the hooded phenotype remained unclear. Recently, the albino mutation has been identified as the Arg299His missense mutation in the Tyrosinase gene and the hooded (H) locus has been mapped to the ∼460-kb region in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.