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Elevated histone acetylations in Müller cell contribute to inflammation: A novel inhibitory effect of minocycline

22 Aug 2012

Abstract excerpt

Inflammation plays important roles in the development of diabetic retinopathy (DR). How Müller cells contribute to DR-related inflammation remains unclear. We hypothesized that under diabetic conditions, elevated histone acetylations in Müller cells contribute to the inflammatory response. In this study, significantly increased histone acetylations, elevated histone acetyltranferases levels, and decreased histone...

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Share to Histone Deacetylase Inhibitors Research
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PMID: 22915469
DOI: 10.1002/glia.22405

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