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Article

Cognitive and behavioral symptoms in Parkinson's disease patients with the G2019S and R1441G mutations of the LRRK2 gene.

Parkinsonism & related disorders - 1 May 2015

Somme Johanne Hatteland, Molano Salazar Ana, Gonzalez Amaia, Tijero Beatriz, Berganzo Koldo, Lezcano Elena, Fernandez Martinez Manuel, Zarranz Juan Jose, Gómez-Esteban Juan Carlos

Abstract excerpt

OBJECTIVE: To compare the cognitive and psychiatric status of patients with Parkinson's disease related to the G2019S and the R1441G mutations of the LRRK2 gene (LRRK2-PD) and idiopathic Parkinson's disease (iPD) patients. METHODS: We examined cognition and psychiatric symptoms in 27 patients with LRRK2-PD (12 G2019S and 15 R1441G) and 27 iPD patients. RESULTS: The groups were similar in age, education, disease...

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PMID: 25840672
DOI: 10.1016/j.parkreldis.2015.02.019

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