Article
The minor spliceosomal protein U11/U12-31K is an RNA chaperone crucial for U12 intron splicing and the development of dicot and monocot plants.
PloS one - 1 Jan 2012
Kwak Kyung Jin, Jung Hyun Ju, Lee Kwang Ho, Kim Young Soon, Kim Won Yong, Ahn Sung Ju, Kang Hunseung
Abstract excerpt
U12 intron-specific spliceosomes contain U11 and U12 small nuclear ribonucleoproteins and mediate the removal of U12 introns from precursor-mRNAs. Among the several proteins unique to the U12-type spliceosomes, an Arabidopsis thaliana AtU11/U12-31K protein has been shown to be indispensible for proper U12 intron splicing and for normal growth and development of Arabidopsis plants. Here, we assessed the functional...
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