Article
Arabidopsis TITAN-LIKE is required for U12-type intron splicing, especially of AT-AC subtypes.
Plant & cell physiology - 5 Sept 2026
Niwa Tomoko, Miyamoto Junshin, Iwase Nao, Iwai Haruka, Kojima Takaaki, Suzuki Takamasa
Abstract excerpt
Many eukaryotes possess two types of spliceosomes: the U2-dependent and U12-dependent spliceosomes. The U2-dependent spliceosome processes >99% of all introns, whereas the U12-dependent spliceosome acts on only ~0.3% of introns, one-third of which start with AT and end with AC, with the remainder having GT-AG termini. How the U12-dependent spliceosome splices two types of introns with different terminal sequences...
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- Arabidopsis
- Introns
- Arabidopsis Proteins
- RNA Splicing
- Mutation
- Spliceosomes
- Gene Expression Regulation, Plant