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Article

Involvement of Membrane GRP78 in Trophoblastic Cell Fusion

9 Aug 2012

Abstract excerpt

BACKGROUND: Glucose-regulated protein 78 (GRP78) is highly expressed in first trimester cytrophoblastic cells (CTBs), especially in syncytiotrophoblast (STB). However, the role of GRP78 in these cells has never been investigated. METHODOLOGY/PRINCIPAL FINDINGS: In this study, we have examined the role of GRP78 in trophoblast fusion using the Bewo choriocarcinoma cell line as a model of cytotrophoblast fusion....

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PMID: 22912664
DOI: 10.1371/journal.pone.0040596

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